Científicos en todo el mundo y su arduo trabajo hacen posible este proyecto. Estas son nuestras referencias; ¡Revísalas para obtener información más detallada!
General Structural Biology Information
1. Protein Data Bank (https://www.rcsb.org)
2. Nature Research (https://www.nature.com/subjects/structural-biology)
3. Structural biology shapes up (Link to Science Feature)
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Spike Protein
1. Structure, Function, and Antigenicity of the SARS-CoV-2 Spike Glycoprotein (Link to Cell Article)
2. Characterization of spike glycoprotein of SARS-CoV-2 on virus entry and its immune cross-reactivity with SARS-CoV (Link to Nature Article)
3. Site-specific glycan analysis of the SARS-CoV-2 spike (Link to Science Article)
ACE2 Receptor
1. Structure of SARS Coronavirus Spike Receptor-Binding Domain Complexed with Receptor (Link to Science Article)
2. Structural basis of receptor recognition by SARS-CoV-2 (Link to Nature Article)
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RNA Polymerase
1. Structural and Biochemical Characterization of the nsp12-nsp7-nsp8 Core Polymerase Complex from SARS-CoV-2 (Link to Cell Article)
2. Structural Basis for RNA Replication by the SARS-CoV-2 Polymerase (Link to Cell Article)
3. Structure of the SARS-CoV nsp12 polymerase bound to nsp7 and nsp8 co-factors (Link to Nature Article)
Main Protease
1. Boceprevir, GC-376, and calpain inhibitors II, XII inhibit SARS-CoV-2 viral replication by targeting the viral main proteaser (Link to bioRxiv Preprint)
2. Structure-based design of antiviral drug candidates targeting the SARS-CoV-2 main protease (Link to Science Article)
3. Crystal structure of SARS-CoV-2 main protease provides a basis for design of improved α-ketoamide inhibitors (Link to Science Article)
Envelope Protein
1. Structural model of the SARS coronavirus E channel in LMPG micelles (Link to BBA Article)
2. Coronavirus envelope protein: current knowledge (Link to Virology Journal Article)
3. The outbreak of SARS-CoV-2 pneumonia calls for viral vaccines (Link to Nature Comment)
Public Health
1. Latest Updates on the 2019 Coronavirus Outbreak (Link to Health Canada)
2. Real-time tracking of pathogen evolution (Link to Nexstrain)
3. World Health Organization-COVID-19 Website (Link to the WHO)
Kids Page Resources
1. Health Canada Resources for Kids and Parents (Link to Health Canada-Resources)
2. Molecular Landscapes by David S. Goodsell -amazing scientific art (Link to PDB101 Page)
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